Michael S Levine Selected Research

Malformations of Cortical Development

1/2020	Paroxysmal Discharges in Tissue Slices From Pediatric Epilepsy Surgery Patients: Critical Role of GABAB Receptors in the Generation of Ictal Activity.
12/2018	Cellular antiseizure mechanisms of everolimus in pediatric tuberous sclerosis complex, cortical dysplasia, and non-mTOR-mediated etiologies.
2/2014	Pacemaker GABA synaptic activity may contribute to network synchronization in pediatric cortical dysplasia.
1/2012	Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex.
7/2010	Comparative study of cellular and synaptic abnormalities in brain tissue samples from pediatric tuberous sclerosis complex and cortical dysplasia type II.
7/2010	Interneurons, GABAA currents, and subunit composition of the GABAA receptor in type I and type II cortical dysplasia.
11/2008	Pyramidal cell responses to gamma-aminobutyric acid differ in type I and type II cortical dysplasia.
1/2007	Immature neurons and GABA networks may contribute to epileptogenesis in pediatric cortical dysplasia.
6/2004	NMDA receptor alterations in neurons from pediatric cortical dysplasia tissue.

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Michael S Levine Research Topics

Disease

34	Huntington Disease (Huntington's Disease) 10/2021 - 12/2004
9	Malformations of Cortical Development 01/2020 - 06/2004
8	Epilepsy (Aura) 01/2020 - 02/2005
6	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2014 - 10/2004
5	Seizures (Absence Seizure) 01/2017 - 01/2002
4	Tuberous Sclerosis (Bourneville's Disease) 01/2020 - 07/2010
4	Parkinson Disease (Parkinson's Disease) 01/2014 - 10/2004
2	Hemimegalencephaly 02/2014 - 02/2006
1	Body Weight (Weight, Body) 01/2021
1	Infarction (Infarctions) 12/2018
1	Neoplasms (Cancer) 12/2018
1	Neurodevelopmental Disorders 10/2018
1	Growth Disorders 10/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 12/2017
1	Hypoglycemia (Reactive Hypoglycemia) 01/2017
1	Autistic Disorder (Autism) 01/2017
1	Weight Loss (Weight Reduction) 01/2016
1	Fragile X Syndrome (Martin Bell Syndrome) 12/2015
1	Dystonia musculorum deformans type 1 06/2015
1	Dystonia (Limb Dystonia) 06/2015
1	Focal Cortical Dysplasia 02/2014
1	Chorea (Rheumatic Chorea) 01/2013
1	Alzheimer Disease (Alzheimer's Disease) 04/2012
1	Hypokinesia (Bradykinesia) 01/2011
1	Disease Progression 02/2009
1	Ischemia 02/2005
1	Synucleinopathies 10/2004

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2002
5	Glutamic Acid (Glutamate)FDA Link 01/2019 - 01/2006
5	gamma-Aminobutyric Acid (GABA)IBA 01/2019 - 12/2004
5	Dopamine (Intropin)FDA LinkGeneric 01/2014 - 06/2010
5	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2010 - 06/2004
4	trans-sodium crocetinate (crocetin)IBA 01/2020 - 07/2010
3	Glucose (Dextrose)FDA LinkGeneric 10/2018 - 02/2005
3	Glutamate Receptors (Glutamate Receptor)IBA 05/2014 - 06/2004
3	Glutamine (L-Glutamine)FDA Link 05/2014 - 06/2008
3	polyglutamineIBA 05/2014 - 04/2007
2	Aminobutyrates (Aminobutyric Acid)IBA 11/2020 - 02/2014
2	Pharmaceutical PreparationsIBA 01/2020 - 01/2012
2	Biomarkers (Surrogate Marker)IBA 01/2017 - 01/2012
2	CholesterolIBA 01/2016 - 12/2015
2	Cholinergic Agents (Cholinergics)IBA 06/2015 - 01/2015
2	GABA-A Receptors (GABA(A) Receptor)IBA 07/2010 - 08/2009
2	alpha-SynucleinIBA 06/2010 - 10/2004
2	N-Methylaspartate (NMDA)IBA 01/2010 - 01/2007
1	CalciumIBA 10/2021
1	Glucose Transporter Type 3IBA 01/2021
1	4-Aminopyridine (4 Aminopyridine)FDA Link 01/2020
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2019
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2019
1	Everolimus FDA Link 12/2018
1	Sirolimus (Rapamycin)FDA Link 12/2018
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 10/2018
1	Therapeutic UsesIBA 01/2018
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2018
1	Insulin (Novolin)FDA Link 01/2017
1	KetonesIBA 01/2016
1	Janus KinasesIBA 12/2015
1	Muscarinic AntagonistsIBA 06/2015
1	GABA Receptors (GABA Receptor)IBA 02/2014
1	Prostaglandins AIBA 02/2014
1	Histone Deacetylase InhibitorsIBA 02/2013
1	Histone Deacetylases (Histone Deacetylase)IBA 02/2013
1	AntioxidantsIBA 01/2013
1	CurcuminIBA 04/2012
1	Amyloid (Amyloid Fibrils)IBA 04/2012
1	Huntingtin ProteinIBA 04/2012
1	coenzyme Q10 (CoQ10)IBA 02/2012
1	SynucleinsIBA 07/2011
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 09/2010
1	MagnesiumIBA 11/2005
1	Potassium Channels (Potassium Channel)IBA 05/2005
1	Oxygen (Dioxygen)IBA 02/2005
1	Nuclear Proteins (Protein, Nuclear)IBA 02/2005
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 12/2004
1	Kainic Acid (Kainate)IBA 01/2002

Therapy/Procedure

2	Ketogenic Diet 10/2018 - 01/2017
2	Therapeutics 01/2017 - 02/2009
1	Transplantation 01/2018
1	Hemispherectomy 02/2006
1	Drug Therapy (Chemotherapy) 10/2004
1	Injections 01/2002